Jeans for Genes Day

Jeans for Genes Day

Droylsden Academy students are continuing the great fundraising effort carried out last week in support of Macmillian Cancer Support by participating in Jeans for Genes Day on Friday 5th October 2012. For one day only Academy students will be able to wear jeans and trainers in exchange for a £1 donation to the charity behind Jeans for Genes day, Genetic Disorders UK. Students are to wear full Academy uniform from the waist up.

What is Genes for Jeans?
Jeans for Genes is a major fundraiser of the children's Medical Research Institute. This includes Jeans for Genes Day, events, exhibitions and other fundraising events throughout the year.

Chances are you probably know someone who has a genetic disease, because one in twenty children are born with some form of genetic fault. There are children with Leukaemia, muscular dystrophy, genetic defects and many other disorders. The scientists at the Children Medical Research Institute are working ton try to prevent these diseases before they occur in children, or where that is not possible to develop better treatments.

Funds raised by Jeans for Genes Day
The money you raise from Jeans for Genes day goes towards the work of these scientists. You will have heard the human genome; we now have the basic outline of our genetic structure. But we don't yet know how all our genes interact, and there is plenty of work still to be done. This type of research benefits children around the world.

The money raised will continue to help other children suffering from genetic differences. Some of the recent works of the CMRI are:

  • Getting Twitchy;
    In 1995 scientists in CMRI's Muscle Development Unit discovered a muscle gene switch! Nerves instruct muscle fibres to become the fast twitch for speed and strength, or a slow twitch for posture and endurance. This research was the first to identify such a twitch in a muscle gene and laid the groundwork for understanding how certain muscle diseases occur.
     
  • Something Fishy;
    While searching for some genes involvedin cancer, CMRI scientists stumbled upon an entirely new human hormone, Stanniocalcin, thought previously only to exist in fish where it controls calcium levels. In Humans, the gene is thought to play a similar role in calcium metabolism and these findings may have crucial implications in understanding disorders of the skeleton such as osteoporosis.
     
  • Killer Cells;
    In 1998, the gene therapy unit also made a promising advance in its laboratory cell culture dish that could lead to a novel way to treat cancer. They succeeded in adding an extra gene to human cancer cells that allows the immune cells of the body to recognise and kill abnormal cells. The immune system usually has trouble recognising cancer cells as they are part of our own body and not seen as ‘foreign'. While there is still a long way to go to refine the technique, this was a major step forward in bringing new and effective cancer treatments to the clinic.

The money that we raise on Friday will go towards further development of theses cures.

Thank you all for your support.

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Droylsden Academy
Manor Road, Droylsden,
Manchester M43 6QD
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